Nowadays, the healthcare systems face many challenges such as the increase in the number of patients, the increase in the hospitalizations rate, and raising the cost of healthcare services. Therefore, several technologies were developed to provide effective solutions for these problems. The microfluidics paper-based analytical devices (µPADs) have a significant role in improving healthcare services. In general, µPADs are one of the points of care solutions that provide fast, reliable, and cost-effective solutions for diagnosing several types of diseases. In this essay, the role of µPADs in the healthcare system will be considered. Also, the fabrication techniques and the detection mechanisms that are used in µPADs will be addressed. Finally, the challenges and prospects for µPADs will be discussed
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