Due to ever increasing demand of safer medicine impetus has been on researches in natural products especially marine products as it is still an untouched field. One such product is sepia ink obtained from cuttlefish present in Mediterranean and Atlantic Ocean. It has a very special place in homeopathic medicine and in traditional Chinese medicine along with its culinary uses. It is mainly composed of eumelanin and degradation studies have revealed it is a copolymer of 5, 6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid. It has tremendous potential in variety of diseases like uterine dysfunction, anticancer, antimicrobial, anti inflammatory activity along with haemopoetic and hepatoprotective effects. Present review aims to assemble various pharmacological activities of sepia ink although deeper insight in its pharmacological potential is required.
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