Novel Class of Hybrid Natural Products Derived from Lupeol (Part-Iii)

Abstract

Novel hybrid lupeol heterocyclics( quinoline ,pyrimidine and pyrazole ) wereprepared.
Triterpene lupeol isolated from plant Crataeva nurvala was chemicallymodified and hybrid
natural products 3a-p, 4a-p, 5a-b, 6e, 7a-ba, 8a-c ,9 and 10 wereevaluated for antimalarial
activity in vitro.

Issue :

2012 Volume-02

Article Category :

Research Article

Article Subject :

Chemistry

Article Authors :

Namita Misra, Satish Kumar, Pritibha Khare, Kanwal Raj

Keywords :

Lupeol, Hybrid Quinolines, Crataeva nurvala, Antimalarials