Exploring the Anti-Cancer Potential of Plant Secondary Metabolites: Mechanisms and Recent Advancements

Abstract:
Secondary metabolites from plants have garnered significant attention due to their implicit anti-cancer parcels, serving as a promising avenue for the development of new remedial agents. These metabolites, including alkaloids, flavonoids, terpenoids, and phenolic composites, retain unique bioactive properties that parade colorful mechanisms of action against cancer cells. Recent studies have stressed the capability of plant-deduced composites to modulate critical signaling pathways involved in cancer inauguration, progression, and metastasis. For case, alkaloids similar topaclitaxel( deduced
from Taxus species) and vincristine( from Catharanthus roseus) have demonstrated strong cytotoxicity against colorful cancer cell lines by converting apoptosis and inhibiting cell proliferation( Yuan et al., 2023; Weng et al., 2023). also, flavonoids and terpenoids have shown anti-inflammatory, inflammatory,
antioxidant, and antiproliferative goods, contributing to cancer chemoprevention and therapy( Kim et al., 2023; Ahmad et al., 2023). This review presents an in-depth analysis of the anti-cancer eventuality of plant secondary metabolites, fastening on their molecular targets, modes of action, and remedial
efficacity. Also, we explore recent advancements in the insulation, structural explication, and synthetic revision of plant-deduced composites to enhance their anticancer parcels(Zhang et al., 2023). The review also discusses the challenges in rephrasing these composites from laboratory studies to clinical operations, as well as the eventuality of integrating them into multi-modal cancer treatments( Singh et al., 2023).