New Spectrophotometric Methods for the Quantitative Estimation of Rivaroxaban in Formulations

Abstract

Rivaroxaban is used as an oral anticoagulant. The quantitative estimation of Rivaroxaban the analytical methods present are of relatively expensive and hence need for the simple analytical methods. In this proposed research work five such new spectrophotometric methods have been developed and applied for routine determination of Rivaroxaban in pharmaceutical formulations and bulk dosage forms. These methods are based on the color formation of the drug on binding with the different reagents. All these method have different linearity ranges. All these method are simple, Accurate, precise and very effective even at low concentrations and used for the quantitive estimation of Rivaroxaban in commercial formulations

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Issue

2012 Volume-02

Article Subject

Chemistry

Keywords

Rivaroxaban, Spectrophotometric Methods, INH, Naptha Quinone sulphate, Haemtoxylin, 2 2 Bipyridine, 4-Amino phenazone.

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