Spectroiphotometric Determination of Deferasirox in Formulations Using Folin-Ciocalteu and Ferric Chloride Reagents

Abstract

A simple, economical, accurate and precise spectrophotometric method has been
developed for the determination of Deferasirox in formulations. The developed method is
based on the formation of colored complex of drug with FC reagent and Ferric chloride,
showed absorption maximums at 753 and 517nm subsequently. For both Beer’s is obeyed in
the concentration range of 8-40 μg/ml. the results of analysis have been validated statistically
and also by recovery studies.

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Issue

2011 Volume-01

Article Subject

Biotechnology

Keywords

Spectrophotometry, Ferric Chloride, FC reagent, 20% Na2CO3 and Deferasirox

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