Synthesis of Cyclobutan-1-One Derivatives by the Reaction of Ketenes with Chalcones

Abstract

The reaction of haloketene and phenylketene with various chalcones and the chemistry of some of the reaction products have been
investigated. The formation of cyclobutanone was taken as an indication that the reaction proceeds by an[2+2] cycloaddition in
concerted mechanism. These all reactions create new opportunities to utilize the unique structures and high reactivity of ketenes for even
greater progress in the future