Tag: Continuous granulation

Abstract Traditionally the manufacturing of pharmaceutical dosage forms has been a batch-wise process and continuous processes have limitedapplications in a pharmaceutical manufacturing plant. However, several factors are stimulating the pharmaceutical industry toinvestigate the opportunities offered by continuous processes. This production method provides an advantage towards quality assuranceas the batch can be accepted or rejected. However, the increasing demand of pharmaceutical solid dosage forms necessitates theproduction of larger volumes of granules, requiring larger equipment. As all conventional machines for wet granulation (high shear andfluidised bed granulation) can only be operated in a batch-wise manner, several attempts have been made to develop continuous wetgranulation techniques. [avf_view name="Article Addons" view-id="66d98451c48e3"]