Abstract During the last few decades much work in the field of natural products of Pharmaceutical significancehas been done throughout the world. The development of science of pharmaceuticals and the hopes for remediesin chronic diseases generated new enthusiasm in the research workers to develop herbal medicines. Use ofindigenous drugs from plant origin forms a major part of complimentary or traditional medicine. These naturalproducts had been indispensably used by many cultures and traditions folklore medicines for thousands of years.They are intensively explored for their bioactive pharmacophores by modern pharmaceutical companies. Theproducts of the plants and the drugs contains some toxic heavy metals which causes serious illness in the livingbeings. In order to evaluate the toxic metals in the medicinal plants an attempt has been made to demonstrate thepresence of Lead and Mercury in the selected medicinal plant, a rare herb Sarcostemma acidum. Monitering theplants for metals is of great importance for the prevention adverse affects on health. [avf_view name="Article Addons" view-id="66d98451c48e3"]